AFP
Peptizyde was developed in response to parents request for a high DPP
IV-containing enzyme product that did not include fruit-based enzymes
such as papain or bromelain. Like Peptizyde, it is a combination of
three different proteolytic enzymes isolated from fungal plant sources.
Each enzyme has a unique set of peptide bonds it prefers to break, so
the combination of these enzymes allows much more efficient means of
quickly and thoroughl...
AFP Peptizyde was developed in response to parents request for a
high DPP IV-containing enzyme product that did not include fruit-based
enzymes such as papain or bromelain. Like Peptizyde, it is a combination
of three different proteolytic enzymes isolated from fungal plant
sources. Each enzyme has a unique set of peptide bonds it prefers to
break, so the combination of these enzymes allows much more efficient
means of quickly and thoroughly breaking down (hydrolyzing) proteins to
its smaller components. The enzymes in AFP Peptizyde� work only on food
proteins, not carbohydrates, fats, or other compounds, and do not
interfere with medications or other supplements (unless they are also
proteins, which is extremely unlikely). AFP Peptizyde� may be used in
combination with other enzyme products, such as HN-Zyme Prime and or
No-Fenol. One would use either Peptizyde or AFP Peptizyde for protein
digestion based on 1) known sensitivities to papain or, 2) a child
objecting to the odor of Peptizyde (which is due to the presence of
papain).
The aminopeptidase enzyme dipeptidyl peptidase IV, or DPP IV, is able
to hydrolyze and inactivate the exorphin peptide, casomorphin. However,
for maximal protein breakdown, it is not useful alone, and should be
combined with other proteases with different and less stringent peptide
bond specificity. For this reason, AFP Peptizyde also contains two other
fungal proteases with high activity in acid conditions. These enzymes
are present in AFP Peptizyde in high amounts for the purpose of quickly
hydrolyzing proteins while the food is still in the stomach. The ability
of AFP Peptizyde� enzymes to withstand the low pH of the stomach and
remain active under acidic conditions allows hydrolysis of casein and
gluten prior to entrance into the small intestine. Casein and gluten, in
the presence of pancreatic enzymes in the duodenum, can produce
exorphin peptides that may be readily absorbed from the intestine (these
peptides are not absorbed from the stomach). AFP Peptizyde supplements
the "normal" hydrolysis of casein, gluten, and other food proteins such
that the exorphin peptides are not produced because the specific
cleavage pattern to produce these peptides is altered.
